Optimizing viable leukocyte sampling from the female genital tract for clinical trials: an international multi-site study.

Optimizing viable leukocyte sampling from the female genital tract for clinical trials: an international multi-site study.

Functional analysis of mononuclear leukocytes in the female genital mucosa is essential for understanding the immunologic effects of HIV vaccines and microbicides at the site of HIV exposure. However, the best female genital tract sampling technique is unclear.We enrolled women from four sites in Af...

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Bibliographic Details
Main Authors: Lyle R McKinnon, Sean M Hughes, Stephen C De Rosa, Jeffrey A Martinson, Jill Plants, Kirsten E Brady, Pamela P Gumbi, Devin J Adams, Lucia Vojtech, Christine G Galloway, Michael Fialkow, Gretchen Lentz, Dayong Gao, Zhiquan Shu, Billy Nyanga, Preston Izulla, Joshua Kimani, Steve Kimwaki, Alfred Bere, Zoe Moodie, Alan L Landay, Jo-Ann S Passmore, Rupert Kaul, Richard M Novak, M Juliana McElrath, Florian Hladik
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3893217?pdf=render

Internet

http://europepmc.org/articles/PMC3893217?pdf=render

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