Design, Synthesis, and Antibacterial Screening of Some Novel Heteroaryl-Based Ciprofloxacin Derivatives as DNA Gyrase and Topoisomerase IV Inhibitors

A novel series of ciprofloxacin hybrids comprising various heterocycle derivatives has been synthesized and structurally elucidated using <sup>1</sup>H NMR, <sup>13</sup>C NMR, and elementary analyses. Using ciprofloxacin as a reference, compounds <b>1</b><b>...

Full description

Bibliographic Details
Main Authors: Lamya H. Al-Wahaibi, Amer A. Amer, Adel A. Marzouk, Hesham A.M. Gomaa, Bahaa G. M. Youssif, Antar A. Abdelhamid
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/5/399