Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I

Magnolia extract is effective for the chemoprevention of oral cancer through its ability to inhibit mitochondrial respiration at complex I

Abstract Background Magnolia extract (ME) is known to inhibit cancer growth and metastasis in several cell types in vitro and in animal models. However, there is no detailed study on the preventive efficacy of ME for oral cancer, and the key components in ME and their exact mechanisms of action are...

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Bibliographic Details
Main Authors: Qi Zhang, Gang Cheng, Jing Pan, Jacek Zielonka, Donghai Xiong, Charles R. Myers, Liang Feng, Song Seok Shin, Young Heui Kim, Dinh Bui, Ming Hu, Brian Bennett, Kathleen Schmainda, Yian Wang, Balaraman Kalyanaraman, Ming You
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Cell Communication and Signaling
Subjects:
Oral cancer
AMPK
STAT3
Complex I
Online Access:http://link.springer.com/article/10.1186/s12964-020-0524-2

Internet

http://link.springer.com/article/10.1186/s12964-020-0524-2

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