A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic development.

RNA interference (RNAi) is a powerful strategy for studying the phenotypic consequences of reduced gene expression levels in model systems. To develop a method for the rapid characterization of the developmental consequences of gene dysregulation, we tested the use of RNAi for "transient transg...

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Bibliographic Details
Main Authors: Bryan C Bjork, Yuko Fujiwara, Shannon W Davis, Haiyan Qiu, Thomas L Saunders, Peter Sandy, Stuart Orkin, Sally A Camper, David R Beier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3002952?pdf=render