New miRNA Signature Heralds Human NK Cell Subsets at Different Maturation Steps: Involvement of miR-146a-5p in the Regulation of KIR Expression

New miRNA Signature Heralds Human NK Cell Subsets at Different Maturation Steps: Involvement of miR-146a-5p in the Regulation of KIR Expression

Natural killer cells are cytotoxic innate lymphoid cells that play an important role for early host defenses against infectious pathogens and surveillance against tumor. In humans, NK cells may be divided in various subsets on the basis of the relative CD56 expression and of the low-affinity FcγRIII...

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Bibliographic Details
Main Authors: Silvia Pesce, Margherita Squillario, Marco Greppi, Fabrizio Loiacono, Lorenzo Moretta, Alessandro Moretta, Simona Sivori, Patrizio Castagnola, Annalisa Barla, Simona Candiani, Emanuela Marcenaro
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
NK cells
miRNA
KIR
CD56bright
CD56dim
NK cell subsets
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02360/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02360/full

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