Longitudinal study revealing motor, cognitive and behavioral decline in a transgenic minipig model of Huntington's disease
Huntington's disease (HD) is an inherited devastating neurodegenerative disease with no known cure to date. Several therapeutic treatments for HD are in development, but their safety, tolerability and efficacy need to be tested before translation to bedside. The monogenetic nature of this disor...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2020-02-01
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Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/13/2/dmm041293 |