S100A8 Promotes Inflammation via Toll-Like Receptor 4 After Experimental Traumatic Brain Injury

IntroductionS100 calcium-binding protein A8 (S100A8) is also known as macrophage-related protein 8, which is involved in various pathological processes in the central nervous system post-traumatic brain injury (TBI), and plays a critical role in inducing inflammatory cytokines. Accumulating evidence...

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Bibliographic Details
Main Authors: Guo-Yuan He, Chen-Hui Zhao, De-Gang Wu, Hao Cheng, Le-An Sun, De-Long Zhang, Xin-Jie Yang, Xi-Ran Fan, Guang-Fu Di, Xiao-Chun Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.616559/full