A sensitive membrane-targeted biosensor for monitoring changes in intracellular chloride in neuronal processes.

Regulation of chloride gradients is a major mechanism by which excitability is regulated in neurons. Disruption of these gradients is implicated in various diseases, including cystic fibrosis, neuropathic pain and epilepsy. Relatively few studies have addressed chloride regulation in neuronal proces...

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Bibliographic Details
Main Authors: Spencer D Watts, Katherine L Suchland, Susan G Amara, Susan L Ingram
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3323644?pdf=render