Using information interaction to discover epistatic effects in complex diseases.

It is widely agreed that complex diseases are typically caused by the joint effects of multiple instead of a single genetic variation. These genetic variations may show stronger effects when considered together than when considered individually, a phenomenon known as epistasis or multilocus interact...

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Bibliographic Details
Main Authors: Orlando Anunciação, Susana Vinga, Arlindo L Oliveira
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3806769?pdf=render