Studies of New Fused Benzazepine as Selective Dopamine D3 Receptor Antagonists Using 3D-QSAR, Molecular Docking and Molecular Dynamics

In recent years, great interest has been paid to the development of compounds with high selectivity for central dopamine (DA) D3 receptors, an interesting therapeutic target in the treatment of different neurological disorders. In the present work, based on a dataset of 110 collected benzazepine (BA...

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Bibliographic Details
Main Authors: Chunzhi Ai, Zhengtao Xiao, Shuwei Zhang, Jing Liu, Yan Li
Format: Article
Language:English
Published: MDPI AG 2011-02-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:http://www.mdpi.com/1422-0067/12/2/1196/