COG Complex complexities: Detailed characterization of a complete set of HEK293T cells lacking individual COG subunits

COG Complex complexities: Detailed characterization of a complete set of HEK293T cells lacking individual COG subunits

The Conserved Oligomeric Golgi complex is an evolutionarily conserved multisubunit tethering complex (MTC) that is crucial for intracellular membrane trafficking and Golgi homeostasis. The COG complex interacts with core vesicle docking and fusion machinery at the Golgi; however, its exact mechanism...

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Bibliographic Details
Main Authors: Jessica eBailey Blackburn, Irina ePokrovskaya, Peter eFisher, Daniel eUngar, Vladimir eLupashin
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Cathepsin D
Glycosylation
Golgi Apparatus
CRISPR
vesicle tethering
HEK293T
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00023/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2016.00023/full

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