The roles of dystroglycan in the nervous system: insights from animal models of muscular dystrophy
Dystroglycan is a cell membrane protein that binds to the extracellular matrix in a variety of mammalian tissues. The α-subunit of dystroglycan (αDG) is heavily glycosylated, including a special O-mannosyl glycoepitope, relying upon this unique glycosylation to bind its matrix ligands. A distinct gr...
Main Authors: | , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2018-12-01
|
Series: | Disease Models & Mechanisms |
Subjects: | |
Online Access: | http://dmm.biologists.org/content/11/12/dmm035931 |