Functions of PDE3 Isoforms in Cardiac Muscle

Isoforms in the PDE3 family of cyclic nucleotide phosphodiesterases have important roles in cyclic nucleotide-mediated signalling in cardiac myocytes. These enzymes are targeted by inhibitors used to increase contractility in patients with heart failure, with a combination of beneficial and adverse...

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Bibliographic Details
Main Authors: Matthew Movsesian, Faiyaz Ahmad, Emilio Hirsch
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Journal of Cardiovascular Development and Disease
Subjects:
Online Access:http://www.mdpi.com/2308-3425/5/1/10