The role of protein kinase-C theta in control of epithelial to mesenchymal transition and cancer stem cell formation

The protein kinase C (PKC) activator phorbol 12-myristate 13-acetate (PMA) induces transition of the epithelial MCF-7 cell line to a mesenchymal phenotype. A subset of the resulting mesenchymal cells has surface markers characteristics of a cancer stem cell (CSC) population. We profiled the transcri...

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Bibliographic Details
Main Authors: Anjum Zafar, Kristine Hardy, Fan Wu, Jasmine Li, Sudha Rao
Format: Article
Language:English
Published: Elsevier 2015-03-01
Series:Genomics Data
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213596014001159