Possible roles of genetic variations in chemotherapy related cardiotoxicity in pediatric acute lymphoblastic leukemia and osteosarcoma

Possible roles of genetic variations in chemotherapy related cardiotoxicity in pediatric acute lymphoblastic leukemia and osteosarcoma

Abstract Background The treatment of acute lymphoblastic leukemia (ALL) and osteosarcoma (OSC) is very effective: the vast majority of patients recover and survive for decades. However, they still need to face serious adverse effects of chemotherapy. One of these is cardiotoxicity which may lead to...

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Bibliographic Details
Main Authors: Judit C. Sági, Bálint Egyed, Andrea Kelemen, Nóra Kutszegi, Márta Hegyi, András Gézsi, Martina Ayaka Herlitschke, Andrea Rzepiel, Lili E. Fodor, Gábor Ottóffy, Gábor T. Kovács, Dániel J. Erdélyi, Csaba Szalai, Ágnes F. Semsei
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
Anthracycline
Cardiotoxicity
Cancer
Genetic polymorphisms
Childhood cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-4629-6

Internet

http://link.springer.com/article/10.1186/s12885-018-4629-6

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