The Degradation Mechanism of Toxic Atractyloside in Herbal Medicines by Decoction

Atractyloside (ATR) is found in many Asteraceae plants that are commonly used as medicinal herbs in China and other eastern Asian countries. ATR binds specifically to the adenine nucleotide translocator in the inner mitochondrial membrane and competitively inhibits ADP and ATP transport. The toxicit...

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Bibliographic Details
Main Authors: Chih-Jui Chang, Anren Hu, Liang-Yu Chen
Format: Article
Language:English
Published: MDPI AG 2013-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/2/2018