Morphological alterations and G0/G1 cell cycle arrest induced by curcumin in human SK-MEL-37 melanoma cells

Morphological alterations and G0/G1 cell cycle arrest induced by curcumin in human SK-MEL-37 melanoma cells

The aim of this work was to study the effect of curcumin on cell cycle in the human SK-MEL-37 melanoma cell line. In addition, morphological and structural analyses were also performed. Flow cytometric analysis showed a G0/G1 arrest at 5 µM after 24 h exposure and a concentration-dependent increase...

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Bibliographic Details
Main Authors: Marcella Lemos Brettas Carneiro, Elaine Paulucio Porfírio, Andréia Hanada Otake, Roger Chammas, Sônia Nair Báo, Lidia Andreu Guillo
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2010-04-01
Series:Brazilian Archives of Biology and Technology
Subjects:
curcumin
melanoma cells
apoptosis
cell cycle
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000200013

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132010000200013

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