GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes

Prior to genome assembly, the raw sequencing reads must be analyzed for assessment of major genome characteristics such as genome size, heterozygosity, and repetitiveness. For this purpose, the authors introduce GenomeScope 2.0, an extension of GenomeScope for polyploid genomes, and Smudgeplot, whic...

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Bibliographic Details
Main Authors: T. Rhyker Ranallo-Benavidez, Kamil S. Jaron, Michael C. Schatz
Format: Article
Language:English
Published: Nature Publishing Group 2020-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-14998-3