GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes
Prior to genome assembly, the raw sequencing reads must be analyzed for assessment of major genome characteristics such as genome size, heterozygosity, and repetitiveness. For this purpose, the authors introduce GenomeScope 2.0, an extension of GenomeScope for polyploid genomes, and Smudgeplot, whic...
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| Format: | Article |
| Language: | English |
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Nature Publishing Group
2020-03-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-020-14998-3 |
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Article |
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doaj-bb7ec6c178e2449d9f0806ad2d30d2eb2021-05-11T09:06:20ZengNature Publishing GroupNature Communications2041-17232020-03-0111111010.1038/s41467-020-14998-3GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomesT. Rhyker Ranallo-Benavidez0Kamil S. Jaron1Michael C. Schatz2Johns Hopkins UniversityUniversity of LausanneJohns Hopkins UniversityPrior to genome assembly, the raw sequencing reads must be analyzed for assessment of major genome characteristics such as genome size, heterozygosity, and repetitiveness. For this purpose, the authors introduce GenomeScope 2.0, an extension of GenomeScope for polyploid genomes, and Smudgeplot, which can estimate a genome’s ploidy.https://doi.org/10.1038/s41467-020-14998-3 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
T. Rhyker Ranallo-Benavidez Kamil S. Jaron Michael C. Schatz |
| spellingShingle |
T. Rhyker Ranallo-Benavidez Kamil S. Jaron Michael C. Schatz GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes Nature Communications |
| author_facet |
T. Rhyker Ranallo-Benavidez Kamil S. Jaron Michael C. Schatz |
| author_sort |
T. Rhyker Ranallo-Benavidez |
| title |
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes |
| title_short |
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes |
| title_full |
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes |
| title_fullStr |
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes |
| title_full_unstemmed |
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes |
| title_sort |
genomescope 2.0 and smudgeplot for reference-free profiling of polyploid genomes |
| publisher |
Nature Publishing Group |
| series |
Nature Communications |
| issn |
2041-1723 |
| publishDate |
2020-03-01 |
| description |
Prior to genome assembly, the raw sequencing reads must be analyzed for assessment of major genome characteristics such as genome size, heterozygosity, and repetitiveness. For this purpose, the authors introduce GenomeScope 2.0, an extension of GenomeScope for polyploid genomes, and Smudgeplot, which can estimate a genome’s ploidy. |
| url |
https://doi.org/10.1038/s41467-020-14998-3 |
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