Accuracy in copy number calling by qPCR and PRT: a matter of DNA.

Accuracy in copy number calling by qPCR and PRT: a matter of DNA.

The possible implication of copy number variation (CNV) in the genetic susceptibility to human disease needs to be assessed using robust methods that can be applied at a population scale. In this report, we analyze the performance of the two major techniques, quantitative PCR (qPCR) and paralog rati...

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Bibliographic Details
Main Authors: Nora Fernandez-Jimenez, Ainara Castellanos-Rubio, Leticia Plaza-Izurieta, Galder Gutierrez, Iñaki Irastorza, Luis Castaño, Juan Carlos Vitoria, Jose Ramon Bilbao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3236783?pdf=render

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http://europepmc.org/articles/PMC3236783?pdf=render

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