Copper-Containing Alloy as Immunoregulatory Material in Bone Regeneration via Mitochondrial Oxidative Stress

Copper-Containing Alloy as Immunoregulatory Material in Bone Regeneration via Mitochondrial Oxidative Stress

In the mammalian skeletal system, osteogenesis and angiogenesis are closely linked by type H vessels during bone regeneration and repair. Our previous studies confirmed the promotion of these processes by copper-containing metal (CCM) in vitro and in vivo. However, whether and how the coupling of an...

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Bibliographic Details
Main Authors: Daorong Xu, Jikun Qian, Xin Guan, Ling Ren, Kaifan Yang, Xuan Huang, Shuyuan Zhang, Yu Chai, Xiaohu Wu, Hangtian Wu, Xianrong Zhang, Ke Yang, Bin Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
316-5Cu stainless steel
type H vessel
M2a macrophage
PDGF-BB
immunoregulation
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.620629/full

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https://www.frontiersin.org/articles/10.3389/fbioe.2020.620629/full

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