Aha1 Exhibits Distinctive Dynamics Behavior and Chaperone-Like Activity

Aha1 Exhibits Distinctive Dynamics Behavior and Chaperone-Like Activity

Aha1 is the only co-chaperone known to strongly stimulate the ATPase activity of Hsp90. Meanwhile, besides the well-studied co-chaperone function, human Aha1 has also been demonstrated to exhibit chaperoning activity against stress-denatured proteins. To provide structural insights for a better unde...

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Bibliographic Details
Main Authors: Huifang Hu, Qing Wang, Jingwen Du, Zhijun Liu, Yiluan Ding, Hongjuan Xue, Chen Zhou, Linyin Feng, Naixia Zhang
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Molecules
Subjects:
Aha1
NMR
dynamics
chaperone-like activity
α-synuclein
Online Access:https://www.mdpi.com/1420-3049/26/7/1943

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https://www.mdpi.com/1420-3049/26/7/1943

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