The impact of KIR/HLA genes on the risk of developing multibacillary leprosy.

BACKGROUND:Killer-cell immunoglobulin-like receptors (KIRs) are a group of regulatory molecules able to activate or inhibit natural killer cells upon interaction with human leukocyte antigen (HLA) class I molecules. Combinations of KIR and HLA may contribute to the occurrence of different immunologi...

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Main Authors: Hugo Vicentin Alves, Amarilis Giaretta de Moraes, Afonso Carrasco Pepineli, Bruna Tiaki Tiyo, Quirino Alves de Lima Neto, Thais da Silva Santos, Jorge Juarez Vieira Teixeira, Eliane P Ambrosio-Albuquerque, Ana Maria Sell, Jeane Eliete Laguila Visentainer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-09-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6762192?pdf=render