Progress in the Development of Eukaryotic Elongation Factor 2 Kinase (eEF2K) Natural Product and Synthetic Small Molecule Inhibitors for Cancer Chemotherapy

Progress in the Development of Eukaryotic Elongation Factor 2 Kinase (eEF2K) Natural Product and Synthetic Small Molecule Inhibitors for Cancer Chemotherapy

Eukaryotic elongation factor 2 kinase (eEF2K or Ca2+/calmodulin-dependent protein kinase, CAMKIII) is a new member of an atypical α-kinase family different from conventional protein kinases that is now considered as a potential target for the treatment of cancer. This protein regulates the phosphory...

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Bibliographic Details
Main Authors: Bin Zhang, Jiamei Zou, Qiting Zhang, Ze Wang, Ning Wang, Shan He, Yufen Zhao, C. Benjamin Naman
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
eEF2K
protein kinase
enzyme inhibitors
natural products
small molecules
cancer therapy
Online Access:https://www.mdpi.com/1422-0067/22/5/2408

Internet

https://www.mdpi.com/1422-0067/22/5/2408

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