Identification of productive and transforming anal intraepithelial neoplasia using immunohistochemical markers p16INK4a and HPV E4
Background: Immunohistochemical (IHC) biomarkers enable standardised, reproducible grading of anal intraepithelial neoplasia (AIN) based on progression of HPV infection from transient productive infection to complete neoplastic transformation. We investigated the expression of IHC biomarker HPV E4,...
Main Authors: | Annemiek Leeman, David Jenkins, Elske Marra, Edyta Pirog, Miekel van de Sandt, Maarten Schim van der Loeff, John Doorbar, Folkert van Kemenade, Chris Meijer, Wim Quint |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2018-06-01
|
Series: | Papillomavirus Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2405852118300661 |
Similar Items
-
Expression of p16 and HPV E4 on biopsy samples and methylation of FAM19A4 and miR124‐2 on cervical cytology samples in the classification of cervical squamous intraepithelial lesions
by: Annemiek Leeman, et al.
Published: (2020-04-01) -
Immunohistochemical characteristic of expression levels of Kі-67, p16INK4a, HPV16 in cervical intraepithelial neoplasia and cervical cancer
by: V. A. Tumanskiy, et al.
Published: (2017-08-01) -
Evaluation of Immunohistochemical Markers, CK17 and SOX2, as Adjuncts to p53 for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia (dVIN)
by: Shatavisha Dasgupta, et al.
Published: (2021-04-01) -
Virological and serological predictors of anal high-grade squamous intraepithelial lesions among HIV-positive men who have sex with men
by: Elske Marra, et al.
Published: (2018-06-01) -
Expression of p16INK4A Protein in Cervical Intraepithelial Neoplasia and Invasive Carcinoma of Uterine Cervix
by: Vatsala Kishore, et al.
Published: (2017-09-01)