Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients

Distinct Mutation Patterns Reveal Melanoma Subtypes and Influence Immunotherapy Response in Advanced Melanoma Patients

The detection of somatic driver mutations by next-generation sequencing (NGS) is becoming increasingly important in the care of advanced melanoma patients. In our study, we evaluated the NGS results of 82 melanoma patients from clinical routine in 2017. Besides determining the tumor mutational burde...

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Bibliographic Details
Main Authors: Franz J. Hilke, Tobias Sinnberg, Axel Gschwind, Heike Niessner, German Demidov, Teresa Amaral, Stephan Ossowski, Irina Bonzheim, Martin Röcken, Olaf Riess, Claus Garbe, Christopher Schroeder, Andrea Forschner
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Cancers
Subjects:
Genome of advanced melanoma
acral
mucosal
uveal
melanoma of unknown origin
tumor mutation burden
Online Access:https://www.mdpi.com/2072-6694/12/9/2359

Internet

https://www.mdpi.com/2072-6694/12/9/2359

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