Treatment of collagen-induced arthritis rat model by using Notch signalling inhibitor

Background: The Notch signalling pathway has been reported to play a key role in rheumatoid arthritis (RA) development. Thus, inhibition of the activation of this signalling pathway may be a promising approach to the treatment of RA. In this study, the Notch signalling inhibitor LY411575, which can...

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Bibliographic Details
Main Authors: Jianhai Chen, Jian Li, Jinqing Chen, Wenxiang Cheng, Jietao Lin, Liqing Ke, Gang Liu, Xueling Bai, Peng Zhang
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X21000048