The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells
Transcription factor (TF) networks are essential for the molecular identity of each cell type. Here, the authors show that TF Nanog utilises multiple molecular strategies to enhance embryonic stem cell self-renewal, which include regulation of chromatin accessibility in the presence of LIF or mainte...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2019-03-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-019-09041-z |