Potential Role of Humoral IL-6 Cytokine in Mediating Pro-Inflammatory Endothelial Cell Response in Amyotrophic Lateral Sclerosis

Potential Role of Humoral IL-6 Cytokine in Mediating Pro-Inflammatory Endothelial Cell Response in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a multifactorial disease with limited therapeutic options. Numerous intrinsic and extrinsic factors are involved in ALS motor neuron degeneration. One possible effector accelerating motor neuron death in ALS is damage to the blood-Central Nervous System barrier...

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Bibliographic Details
Main Authors: Svitlana Garbuzova-Davis, Jared Ehrhart, Paul R. Sanberg, Cesario V. Borlongan
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:International Journal of Molecular Sciences
Subjects:
ALS
IL-6 cytokine
endothelial cells
inflammation
Online Access:http://www.mdpi.com/1422-0067/19/2/423

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http://www.mdpi.com/1422-0067/19/2/423

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