Methods to investigate intrathecal adaptive immunity in neurodegeneration
Abstract Background Cerebrospinal fluid (CSF) provides basic mechanical and immunological protection to the brain. Historically, analysis of CSF has focused on protein changes, yet recent studies have shed light on cellular alterations. Evidence now exists for involvement of intrathecal T cells in t...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2021-01-01
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Series: | Molecular Neurodegeneration |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13024-021-00423-w |