Hypoxia and glucose metabolism assessed by FMISO and FDG PET for predicting IDH1 mutation and 1p/19q codeletion status in newly diagnosed malignant gliomas

Hypoxia and glucose metabolism assessed by FMISO and FDG PET for predicting IDH1 mutation and 1p/19q codeletion status in newly diagnosed malignant gliomas

Abstract Background Tumor hypoxia and glycolysis have been recognized as determinant factors characterizing tumor aggressiveness in malignant gliomas. To clarify in vivo hypoxia and glucose metabolism in relation to isocitrate dehydrogenase (IDH) mutation and chromosome 1p and 19q (1p/19q) codeletio...

Full description

Bibliographic Details
Main Authors: Kenta Suzuki, Nobuyuki Kawai, Tomoya Ogawa, Keisuke Miyake, Aya Shinomiya, Yuka Yamamoto, Yoshihiro Nishiyama, Takashi Tamiya
Format: Article
Language:English
Published: SpringerOpen 2021-07-01
Series:EJNMMI Research
Subjects:
Chromosome 1p and 19q codeletion
[18F]-Fluoromisonidazole (FMISO)
[18F]-Fluoro-2-deoxy-d-glucose (FDG)
Glioma
IDH mutation
Hypoxia
Online Access:https://doi.org/10.1186/s13550-021-00806-6

Internet

https://doi.org/10.1186/s13550-021-00806-6

Similar Items