Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.

Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.

IWS1 is an RNA-polymerase II (RNAPII)-associated transcription elongation factor whose biological functions are poorly characterized. To shed some light on the function of this protein at the organismal level, we performed a systematic tissue analysis of its expression and generated Iws1-deficient m...

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Bibliographic Details
Main Authors: Arturo Orlacchio, Aaron E Stark, Claudia Foray, Foued Amari, Tyler Sheetz, Erika Reese, Anna Tessari, Krista La Perle, Dario Palmieri, Philip N Tsichlis, Vincenzo Coppola
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0201030

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https://doi.org/10.1371/journal.pone.0201030

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