Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice.

Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice.

Transmembrane adaptor proteins (TRAPs) are important organisers for the transduction of immunoreceptor-mediated signals. Prr7 is a TRAP that regulates T cell receptor (TCR) signalling and potently induces cell death when overexpressed in human Jurkat T cells. Whether endogenous Prr7 has a similar fu...

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Bibliographic Details
Main Authors: Matous Hrdinka, Kritika Sudan, Sissy Just, Ales Drobek, Ondrej Stepanek, Dirk Schlüter, Dirk Reinhold, Bryen A Jordan, Patricia Gintschel, Burkhart Schraven, Michael R Kreutz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5033326?pdf=render

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http://europepmc.org/articles/PMC5033326?pdf=render

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