Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach

Lipidation of Temporin-1CEb Derivatives as a Tool for Activity Improvement, Pros and Cons of the Approach

The alarming raise of multi-drug resistance among human microbial pathogens makes the development of novel therapeutics a priority task. In contrast to conventional antibiotics, antimicrobial peptides (AMPs), besides evoking a broad spectrum of activity against microorganisms, could offer additional...

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Bibliographic Details
Main Authors: Paulina Kosikowska-Adamus, Emilia Sikorska, Dariusz Wyrzykowski, Aleksandra Walewska, Anna Golda, Milena Deptuła, Michał Obuchowski, Adam Prahl, Michał Pikuła, Adam Lesner
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:International Journal of Molecular Sciences
Subjects:
antimicrobial peptides
membranolytic properties of peptides
lipidation of peptides
mode of action of lipopeptides
AMP activity improvement
Online Access:https://www.mdpi.com/1422-0067/22/13/6679

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https://www.mdpi.com/1422-0067/22/13/6679

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