Role of interferon therapy in severe COVID-19: the COVIFERON randomized controlled trial

Role of interferon therapy in severe COVID-19: the COVIFERON randomized controlled trial

Abstract Type 1 Interferons (IFNs) have been associated with positive effects on Coronaviruses. Previous studies point towards the superior potency of IFNβ compared to IFNα against viral infections. We conducted a three-armed, individually-randomized, open-label, controlled trial of IFNβ1a and IFNβ1...

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Main Authors: Ilad Alavi Darazam, Shervin Shokouhi, Mohamad Amin Pourhoseingholi, Seyed Sina Naghibi Irvani, Majid Mokhtari, Minoosh Shabani, Mahdi Amirdosara, Parham Torabinavid, Maryam Golmohammadi, SayedPayam Hashemi, Arsalan Azimi, Mohammad Hossein Jafarazadeh Maivan, Omidvar Rezaei, Alireza Zali, Mohammadreza Hajiesmaeili, Hadiseh Shabanpour Dehbsneh, Akram Hoseyni Kusha, Maryam Taleb Shoushtari, Negar Khalili, Azam Soleymaninia, Latif Gachkar, Ali Khoshkar
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86859-y

Internet

https://doi.org/10.1038/s41598-021-86859-y

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