Research advances in animal models of hepatitis B virus infection
For the ideal preclinical animal model of hepatitis B virus (HBV), its hepatocytes should allow HBV entry and cccDNA generation and have both innate and adaptive immune systems. However, HBV only naturally infects humans and chimpanzees due to highly restricted species specificity, and no effective...
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Format: | Article |
Language: | zho |
Published: |
Editorial Department of Journal of Clinical Hepatology
2021-05-01
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Series: | Linchuang Gandanbing Zazhi |
Online Access: | http://www.lcgdbzz.org/cn/article/doi/10.3969/j.issn.1001-5256.2021.05.002 |