Research advances in animal models of hepatitis B virus infection

For the ideal preclinical animal model of hepatitis B virus (HBV), its hepatocytes should allow HBV entry and cccDNA generation and have both innate and adaptive immune systems. However, HBV only naturally infects humans and chimpanzees due to highly restricted species specificity, and no effective...

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Bibliographic Details
Main Author: YANG Weifeng
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Hepatology 2021-05-01
Series:Linchuang Gandanbing Zazhi
Online Access:http://www.lcgdbzz.org/cn/article/doi/10.3969/j.issn.1001-5256.2021.05.002