CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans

CD49a Expression Identifies a Subset of Intrahepatic Macrophages in Humans

Macrophages play central roles in inflammatory reactions and initiation of immune responses during infections. More than 80% of total tissue macrophages are described to be located in the liver as liver-resident macrophages, also named Kupffer cells (KCs). While studies in mice have established a ce...

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Bibliographic Details
Main Authors: Glòria Martrus, Hanna Goebels, Annika E. Langeneckert, Janine Kah, Felix Flomm, Annerose E. Ziegler, Annika Niehrs, Sebastian M. Löbl, Kristina Russu, Leonard U. Hess, Wilhelm Salzberger, Tobias Poch, Björn Nashan, Christoph Schramm, Karl J. Oldhafer, Maura Dandri, Martina Koch, Sebastian Lunemann, Marcus Altfeld
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Immunology
Subjects:
monocytes/macrophages
human liver
tissue residency
cell activation
CD49a
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01247/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01247/full

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