Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV‐CATCHER): A customizable purification assay designed for small‐RNA biomarker identification and evaluation of circulating small‐EVs

Extracellular Vesicle Capture by AnTibody of CHoice and Enzymatic Release (EV‐CATCHER): A customizable purification assay designed for small‐RNA biomarker identification and evaluation of circulating small‐EVs

Abstract Circulating nucleic acids, encapsulated within small extracellular vesicles (EVs), provide a remote cellular snapshot of biomarkers derived from diseased tissues, however selective isolation is critical. Current laboratory‐based purification techniques rely on the physical properties of sma...

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Bibliographic Details
Main Authors: Megan I. Mitchell, Iddo Z. Ben‐Dov, Christina Liu, Kenny Ye, Kar Chow, Yael Kramer, Anju Gangadharan, Steven Park, Sean Fitzgerald, Andrew Ramnauth, David S. Perlin, Michele Donato, Emily Bhoy, Ehsan Manouchehri Doulabi, Michael Poulos, Masood Kamali‐Moghaddam, Olivier Loudig
Format: Article
Language:English
Published: Taylor & Francis Group 2021-06-01
Series:Journal of Extracellular Vesicles
Subjects:
exosome purification
extracellular vesicles
micro‐RNA profiling
sequencing
TEM
Online Access:https://doi.org/10.1002/jev2.12110

Internet

https://doi.org/10.1002/jev2.12110

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