Sensitive Automated Measurement of Histone-DNA Affinities in Nucleosomes

Summary: The DNA of eukaryotes is wrapped around histone octamers to form nucleosomes. Although it is well established that the DNA sequence significantly influences nucleosome formation, its precise contribution has remained controversial, partially owing to the lack of quantitative affinity data....

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Bibliographic Details
Main Authors: Max Schnepf, Claudia Ludwig, Peter Bandilla, Stefano Ceolin, Ulrich Unnerstall, Christophe Jung, Ulrike Gaul
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220300079