A prospective, open-label, non-comparative study of ambrisentan with anti-fibrotic agent combination therapy in the treatment of diffuse systemic sclerosis

Abstract Background Systemic Sclerosis is a multifactorial autoimmune rheumatic disease characterized by inflammation, fibrosis, immune dysregulation and vascular dysfunction. Methods An open label, prospective, non-comparative study evaluating ambrisentan with an antifibrotic agent in diffuse cutan...

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Bibliographic Details
Main Authors: Annemarie Schorpion, Max Shenin, Robin Neubauer, Chris T. Derk
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Rheumatology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41927-018-0021-z