Soluble RAGE Treatment Delays Progression of Amyotrophic Lateral Sclerosis in SOD1 Mice
The etiology of amyotrophic lateral sclerosis (ALS), a fatal motor neuron disorder characterized by progressive muscle weakness and spasticity, remains largely unknown. Approximately 5-10% of cases are familial, and of those, 15-20% are associated with mutations in the gene encoding Cu/Zn superoxide...
Main Authors: | Judyta K Juranek, Gurdip K Daffu, Matthew S Geddis, Huilin eLi, Rosa eRosario, Benjamin S Kaplan, Lauren eKelly, Ann Marie eSchmidt |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-05-01
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Series: | Frontiers in Cellular Neuroscience |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00117/full |
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