Knock-Out of Tenascin-C Ameliorates Ischemia-Induced Rod-Photoreceptor Degeneration and Retinal Dysfunction

Knock-Out of Tenascin-C Ameliorates Ischemia-Induced Rod-Photoreceptor Degeneration and Retinal Dysfunction

Retinal ischemia is a common pathomechanism in various eye diseases. Recently, evidence accumulated suggesting that the extracellular matrix (ECM) glycoprotein tenascin-C (Tnc) plays a key role in ischemic degeneration. However, the possible functional role of Tnc in retinal ischemia is not yet know...

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Bibliographic Details
Main Authors: Susanne Wiemann, Aisha Yousf, Stephanie C. Joachim, Carolin Peters, Ana M. Mueller-Buehl, Natalie Wagner, Jacqueline Reinhard
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Neuroscience
Subjects:
electroretinography
extracellular matrix
ischemia/reperfusion
retina
rod-bipolar cells
rod-photoreceptor cells
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.642176/full

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https://www.frontiersin.org/articles/10.3389/fnins.2021.642176/full

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