Plasminogen activator inhibitor-1 is involved in impaired bone repair associated with diabetes in female mice.

Previous studies suggest that fracture healing is impaired in diabetes; however, the underlying mechanism remains unclear. Here, we investigated the roles of plasminogen activator inhibitor-1 (PAI-1) in the impaired bone repair process by using streptozotocin (STZ)-induced diabetic female wild-type...

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Bibliographic Details
Main Authors: Li Mao, Naoyuki Kawao, Yukinori Tamura, Katsumi Okumoto, Kiyotaka Okada, Masato Yano, Osamu Matsuo, Hiroshi Kaji
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3961397?pdf=render