Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance

Evolutionary engineering in Saccharomyces cerevisiae reveals a TRK1-dependent potassium influx mechanism for propionic acid tolerance

Abstract Background Propionic acid (PA), a key platform chemical produced as a by-product during petroleum refining, has been widely used as a food preservative and an important chemical intermediate in many industries. Microbial PA production through engineering yeast as a cell factory is a potenti...

Full description

Bibliographic Details
Main Authors: Xin Xu, Thomas C. Williams, Christina Divne, Isak S. Pretorius, Ian T. Paulsen
Format: Article
Language:English
Published: BMC 2019-04-01
Series:Biotechnology for Biofuels
Subjects:
Adaptive laboratory evolution
Organic acid tolerance
Propionic acid
TRK1
Potassium uptake
Yeast
Online Access:http://link.springer.com/article/10.1186/s13068-019-1427-6

Internet

http://link.springer.com/article/10.1186/s13068-019-1427-6

Similar Items