Sulfatide decreases the resistance to stress-induced apoptosis and increases P-selectin-mediated adhesion: a two-edged sword in breast cancer progression

Sulfatide decreases the resistance to stress-induced apoptosis and increases P-selectin-mediated adhesion: a two-edged sword in breast cancer progression

Abstract Background We have previously shown that galactosylceramide (GalCer) affects the tumourigenic and metastatic properties of breast cancer cells by acting as an anti-apoptotic molecule. Since GalCer is a precursor molecule in the synthesis of sulfatides, the present study was aimed to define...

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Bibliographic Details
Main Authors: Jaroslaw Suchanski, Jedrzej Grzegrzolka, Tomasz Owczarek, Pawel Pasikowski, Aleksandra Piotrowska, Bartlomiej Kocbach, Aleksandra Nowak, Piotr Dziegiel, Andrzej Wojnar, Maciej Ugorski
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Sulfatide
Galactosyloceramide
Apoptosis
Platelets
P-selectin
Online Access:http://link.springer.com/article/10.1186/s13058-018-1058-z

Internet

http://link.springer.com/article/10.1186/s13058-018-1058-z

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