PHF19 mediated regulation of proliferation and invasiveness in prostate cancer cells

The Polycomb-like protein PHF19/PCL3 associates with PRC2 and mediates its recruitment to chromatin in embryonic stem cells. PHF19 is also overexpressed in many cancers. However, neither PHF19 targets nor misregulated pathways involving PHF19 are known. Here, we investigate the role of PHF19 in pros...

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Bibliographic Details
Main Authors: Payal Jain, Cecilia Ballare, Enrique Blanco, Pedro Vizan, Luciano Di Croce
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/51373