Drug Response-Related DNA Methylation Changes in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Drug Response-Related DNA Methylation Changes in Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Pharmacotherapy is the most common treatment for schizophrenia (SCZ), bipolar disorder (BD), and major depressive disorder (MDD). Pharmacogenetic studies have achieved results with limited clinical utility. DNA methylation (DNAm), an epigenetic modification, has been proposed to be involved in both...

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Bibliographic Details
Main Authors: Jiaqi Zhou, Miao Li, Xueying Wang, Yuwen He, Yan Xia, John A. Sweeney, Richard F. Kopp, Chunyu Liu, Chao Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Neuroscience
Subjects:
pharmacoepigenetic
DNA methylation
drug response
schizophrenia
bipolar disorder
major depressive disorder
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.674273/full

Internet

https://www.frontiersin.org/articles/10.3389/fnins.2021.674273/full

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