Diagnostic performance of an Aspergillus-specific nested PCR assay in cerebrospinal fluid samples of immunocompromised patients for detection of central nervous system aspergillosis.

Diagnostic performance of an Aspergillus-specific nested PCR assay in cerebrospinal fluid samples of immunocompromised patients for detection of central nervous system aspergillosis.

Central nervous system (CNS) invasive aspergillosis (IA) is a fatal complication in immunocompromised patients. Confirming the diagnosis is rarely accomplished as invasive procedures are impaired by neutropenia and low platelet count. Cerebrospinal fluid (CSF) cultures or galactomannan (GM) regularl...

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Bibliographic Details
Main Authors: Mark Reinwald, Dieter Buchheidt, Margit Hummel, Matthias Duerken, Hartmut Bertz, Rainer Schwerdtfeger, Stefan Reuter, Michael G Kiehl, Manuel Barreto-Miranda, Wolf-Karsten Hofmann, Birgit Spiess
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3579826?pdf=render

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http://europepmc.org/articles/PMC3579826?pdf=render

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