Identification of ALK gene alterations in urothelial carcinoma.

BACKGROUND: Anaplastic lymphoma kinase (ALK) genomic alterations have emerged as a potent predictor of benefit from treatment with ALK inhibitors in several cancers. Currently, there is no information about ALK gene alterations in urothelial carcinoma (UC) and its correlation with clinical or pathol...

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Main Authors: Joaquim Bellmunt, Shamini Selvarajah, Scott Rodig, Marta Salido, Silvia de Muga, Irmgard Costa, Beatriz Bellosillo, Lillian Werner, Stephanie Mullane, André P Fay, Robert O'Brien, Jordi Barretina, André E Minoche, Sabina Signoretti, Clara Montagut, Heinz Himmelbauer, David M Berman, Philip Kantoff, Toni K Choueiri, Jonathan E Rosenberg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4118868?pdf=render