Altered cytoskeletal arrangement in induced pluripotent stem cells and motor neurons from patients with riboflavin transporter deficiency

Altered cytoskeletal arrangement in induced pluripotent stem cells and motor neurons from patients with riboflavin transporter deficiency

The cytoskeletal network plays a crucial role in the differentiation, morphogenesis, function and homeostasis of the nervous tissue, so that alterations in any of its components may lead to neurodegenerative diseases. Riboflavin transporter deficiency (RTD), a childhood-onset disorder characterized...

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Bibliographic Details
Main Authors: Alessia Niceforo, Chiara Marioli, Fiorella Colasuonno, Stefania Petrini, Keith Massey, Marco Tartaglia, Enrico Bertini, Sandra Moreno, Claudia Compagnucci
Format: Article
Language:English
Published: The Company of Biologists 2021-02-01
Series:Disease Models & Mechanisms
Subjects:
riboflavin transporter deficiency
ipscs
motor neurons
tubulin
riboflavin
nac
Online Access:http://dmm.biologists.org/content/14/2/dmm046391

Internet

http://dmm.biologists.org/content/14/2/dmm046391

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